It used to be…fairly easy to get a proposal through IRB. Now it is easier to write the grant proposal than the IRB proposal.
Anonymous researcher1
Background
Stamina and mental fortitude are necessary attributes for the present‐day researcher seeking approval from his institution's human subjects protection review board (IRB). Both popular media and respected journals continue to report extremely rare but serious harms to research subjects as well as overly bureaucratic IRB responses. This leads to a pervasive perception of IRB overregulation yet underprotection of human subjects.2 Although the Office for Human Research Protections (OHRP) reports that



